Genome of Halomonas Strain GFAJ-1, a Blueprint for Fame or Business as Usual

Genome of halomonas strain GFAJ-1, a blueprint for fame or business as usual.

Draft genome of halomonas species strain GFAJ-1 (ATCC BAA-2256).

Halomonas strain GFAJ-1 was reported in Science magazine to be a remarkable microbe for which there was "arsenate in macromolecules that normally contain phosphate, most notably nucleic acids." The draft genome of the bacterium was determined (NCBI accession numbers AHBC01000001 through AHBC01000103). It appears to be a typical gamma proteobacterium.

Pharmacotherapy for borderline patients: business as usual or by default?

In their analysis of a representative sample from the Prescribing Observatory for Mental Health in the UK health services, Paton et al found that 92% of patients with borderline personality disorder (BPD) received prescriptions for psychotropic medications. Although international guidelines recommend pharmacotherapy for comorbid psychiatric disorders whenever necessary, 82% of the UK BPD patien...

Curriculum for Excellence: transformational change or business as usual?

Scotland’s Curriculum for Excellence (CfE) is a good example of a new breed of national curriculum; a curricular model that seeks to combine top-down government prescription with bottom-up school-based curriculum development by teaching professionals. However, in developing a renewed view of teachers as agents of change and relaxing curriculum prescription, CfE has attracted criticism for its v...

A blueprint of ectoine metabolism from the genome of the industrial producer Halomonas elongata DSM 2581T

The halophilic γ-proteobacterium Halomonas elongata DSM 2581(T) thrives at high salinity by synthesizing and accumulating the compatible solute ectoine. Ectoine levels are highly regulated according to external salt levels but the overall picture of its metabolism and control is not well understood. Apart from its critical role in cell adaptation to halophilic environments, ectoine can be used ...